The role of the PHB complex in mitochondrial biogenesis

Thesis

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Titlepage

Table of Contents

Abbreviations

1 Introduction

2 The mitochondrial PHB complex: roles in mitochondrial respiratory complex assembly, ageing and degenerative disease

3 Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins

4 A structure for the yeast prohibitin complex: Structure prediction and evidence from chemical crosslinking and mass spectrometry

5 The mitochondrial prohibitin complex is essential for embryonic viability and germline function in Caenorhabditis elegans

6 General discussion

Summary

Samenvatting

Resumen

Acknowledgements

List of publications

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