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  2. Imprinting and gene silencing are in the Air

Imprinting and gene silencing are in the Air

Open Access
Authors
  • F.J.G.T. Sleutels
Supervisors
  • A.J.M. Berns
Cosupervisors
  • D.P. Barlow
Award date 26-10-2001
Number of pages 143
Organisations
  • Faculty of Medicine (AMC-UvA)
Document type PhD thesis
Note Research conducted at: NKI
Language English
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Thesis
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Titlepage
Contents
Chapter 1 The origins of genomic imprinting in mammals
Chapter 2 Investigation of elements sufficient to imprint the mouse Air promoter
Chapter 3 Bi-directional action of the Igf2r imprint control element on upstream and downstream imprinted genes.
Chapter 4 The non-coding RNA Air silences a domain of autosomal imprinted genes revealing mechanistic parallels with X chromosome inactivation
Chapter 5 Imprinting of the Slc22a2 and Slc22a3 genes by the non-coding Air RNA does not require transcriptional overlap with the linked Igf2r locus
Chapter 6 Summarizing discussion
Nederlandse samenvatting
Dankwoord
Curriculum Vitae
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