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Results: 83
Number of items: 83
  • Bachmann, I. M., Halvorsen, O. J., Collett, K., Stefansson, I. M., Straume, O., Haukaas, S. A., Salvesen, H. B., Otte, A. P., & Akslen, L. A. (2006). EZH2 expression is associated with high proliferation rate and aggresive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast. Journal of Clinical Oncology, 24, 268-273. https://doi.org/10.1200/JCO.2005.01.5180
  • Collett, K., Eide, G. E., Arnes, J., Stefansson, I. M., Eide, J., Braaten, A., Aas, T., Otte, A. P., & Akslen, L. A. (2006). Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggresive breast cancer. Clinical Cancer Research, 12, 1168-1174. https://doi.org/10.1158/1078-0432.CCR-05-1533
  • Lee, T. I., Jenner, R. G., Boyer, L. A., Guenther, M. G., Levine, S. S., Kumar, R. M., Chevalier, B., Johnstone, S. E., Cole, M. F., Isono, K., Koseki, H., Fuchikami, T., Abe, K., Murray, H. L., Zucker, J. P., Yuan, B., Bell, G. W., Herbolsheimer, E., Hannett, N. M., ... Young, R. A. (2006). Control of developmental regulators by Polycomb in human embryonic stem cells. Cell, 125, 301-313. https://doi.org/10.1016/j.cell.2006.02.043
  • Boyer, L. A., Plath, K., Zeitlinger, J., Brambrink, T., Medeiros, L. A., Lee, T. I., Levine, S. S., Wernig, M., Tajonar, A., Ray, M. K., Bell, G. W., Otte, A. P., Vidal, M., Gifford, D. K., Young, R. A., & Jaenisch, R. (2006). Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature, 441, 349-353. https://doi.org/10.1038/nature04733
  • Fujimura, Y., Isono, K., Vidal, M., Endoh, M., Kajita, H., Mizutani-Koseki, Y., Takihara, Y., van Lohuizen, M., Otte, A. P., Jenuwein, T., Deschamps, J., & Koseki, H. (2006). Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8. Development - The Company of Biologists, 133, 2371-2381. https://doi.org/10.1242/dev.02405
  • Kwaks, T. H. J., & Otte, A. P. (2006). Employing epigenetics to augment the expression of therapeutic proteins in mammalian cells. Trends in Biotechnology, 24(3), 137-142. https://doi.org/10.1016/j.tibtech.2006.01.007
  • Breuer, R. H. J., Snijders, P. J. F., Sutedja, T. G., Sewalt, R. G. A. B., Otte, A. P., Postmus, P. E., Meijer, C. J. L. M., Raaphorst, F. M., & Smit, E. F. (2005). Expression of the p16(INK4a) gene product, methylation of the p16(INK4a) promoter region and expression of the polycomb-group gene BMI-1 in squamous cell lung carcinoma and premalignant endobronchial lesions. Lung Cancer, 48, 299-306. https://doi.org/10.1016/j.lungcan.2004.11.026
  • Montgomery, N. D., Yee, D., Chen, A., Kalantry, S., Chamberlain, S. J., Otte, A. P., & Magnuson, T. (2005). The murine polycomb group protein Eed is required for global histone H3 lysine-27 methylation. Current Biology, 15, 942-947. https://doi.org/10.1016/j.cub.2005.04.051
  • Okamoto, I., Arnaud, D., Le Baccon, P., Otte, A. P., Disteche, C. M., Avner, P., & Heard, E. (2005). Evidence for de novo imprinted X-cgromosome inactivation independent of meiotic inactivation in mice. Nature, 438, 369-373. https://doi.org/10.1038/nature04155
  • Cha, T.-L., Zhou, B. P., Xia, W., Wu, Y. L., Yang, C.-C., Chen, C.-T., Ping, B., Otte, A. P., & Hung, M.-C. (2005). Akt-mediated phosphorylation of EZH2 augments methylation of lysine 27 in histone H3. Science, 310, 306-310. https://doi.org/10.1126/science.1118947
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