Oncogenic and metastatic functions of the neurotrophic receptor TRKB

T.R. Geiger

Oncogenic and metastatic functions of the neurotrophic receptor TRKB

Authors	T.R. Geiger
Supervisors	A.J.M. Berns D.S. Peeper
Award date	19-12-2008
ISBN	9789075575163
Number of pages	147
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	A modified version of chapter 1 has been published in BBA Reviews on Cancer (Biochim Biophys Acta. 2009 Dec;1796(2):293-308. Epub 2009 Aug 14. doi:10.1016/j.bbcan.2009.07.006. Title: Metastasis mechanisms. Authors: Geiger TR, Peeper DS.). A modified version of chapter 4 has been published in PLoS ONE (PLoS One. 2011 Feb 17;6(2):e16871, doi:10.1371/journal.pone.0016871. Functional characterization of human cancer-derived TRKB mutations. Geiger TR, Song JY, Rosado A, Peeper DS). Parts of chapter 5 have been published in the Jounal of Molecular and Cellular Biology of the American Society for Microbiology (Mol Cell Biol. 2009 Jul;29(13):3722-37. Epub 2009 May 4). For the definitive version, see: doi:10.1128/MCB.01164-08. Copyright © 2009, American Society for Microbiology. All rights reserved. Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Cover Title page Contents Scope of this thesis Chapter 1: Metastasis mechanisms Chapter 2: The neurotrophic receptor TRKB in anoikis resistance, tumorigenesis and metastasis Chapter 3: Critical role for TRKB kinase function in anoikis suppression, tumorigenesis and metastasis Chapter 4: Functional characterization of human cancer-derived TRKB mutants Chapter 5: A twist–snail axis critical for TRKB-induced EMT, anoikis resistance and metastasis Chapter 6: General discussion List of abbreviations Nederlandstalige samenvatting English summary Deutsche Zusammenfassung Curriculum vitae and publications Acknowledgments Back matter
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Oncogenic and metastatic functions of the neurotrophic receptor TRKB