Viro-immunological studies on the role of Epstein-Barr virus in the development of AIDS-related non-Hodgekin's lymphoma

Thesis

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Titlepage

Table of Contents

Chapter 1 General introduction

Part I Virological studies

Chapter 2 Direct Epstein-Barr virus (EBV) typing on peripheral blood mononuclear cells: No association between EBV type 2 infection or superinfection and the development of acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma

Chapter 3 High prevalence of Epstein-Barr virus type 2 among homosexual men is caused by sexual transmission

Chapter 4 Epstein-Barr virus (EBV) load in Human immunodeficiency virus-1 infection is not predictive of AIDS-related non-Hodgkin's lymphoma

Part II Immunological studies

Chapter 5 Dysfunctional Epstein-Barr virus (EBV)-specific CD8⁺ T lymphocytes and increased EBV load in AIDS-related non-Hodgkin's lymphoma patients

Chapter 6 Lack of differentiation of virus-specific CD8⁺ T cells into CD27⁻ effector cells is associated with progression to clinical disease

Chapter 7 Differential restoration of functional Epstein-Barr virus and Human immunodeficiency virus specific CD8⁺ T cells during antiretroviral therapy

Part III: Viro-immunological aspects

Chapter 8 General Discussion

Summary

Nederlandse samenvatting voor niet-ingewijden

List of publications

Curriculum Vitae

Nawoord

Stellingen behorende bij het proefschift

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