Barrett’s esophagus Risk factors, risk stratification and treatment

Thesis (complete)

Front matter

Chapter 1: Use of smokeless tobacco and cigar/pipe smoking are risk factors for Barrett’s esophagus in male GERD patients

Chapter 2: The Y-chromosome F haplogroup contributes to the development of Barrett’s esophagus associated esophageal adenocarcinoma in a white male population

Chapter 3: Derivation of genetic biomarkers for cancer risk stratification in Barrett’s oesophagus: A prospective cohort study

Chapter 4: Single cell genetic diversity predicts progression to esophageal adenocarcinoma in patients with high-risk mucosal lesions in Barrett’s esophagus

Chapter 5: Inhibition of the BMP pathway prevents development of Barrett’s associated adenocarcinoma in a surgical rat model

Summary and general discussion

Nederlandse samenvatting

Abbreviations; Contributing authors; List of publications; PhD portfolio; Acknowledgments/Dankwoord; About the author