Genetic markers in malignant progression of Barrett’s esophagus

Authors	A.M. Rygiel
Supervisors	M.P. Peppelenbosch P. Fockens
Cosupervisors	K.K. Krishnadath J.J.G.H. Bergman
Award date	18-01-2008
ISBN	9789064641800
Number of pages	147
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Titlepage Contents Chapter 1 General introduction and outline of the thesis Chapter 2 Efficient automated assessment of genetic abnormalities detected by Fluorescent in situ hybridization on brush cytology of a Barrett’s esophagus surveillance population Chapter 3 Assessment of chromosomal gains as compared to DNA content changes is more useful to detect dysplasia in Barrett’s esophagus brush cytology specimens Chapter 4 Sequential chromosomal event preceding Her-2 protooncogene Chapter 5 Low level of Her-2 locus amplification by Fluorescent in situ hybridization does not correlate with strong Her-2 protein overexpression by Immunohistochemistry in Barrett’s esophagus Chapter 6 Gains and amplifications of c-myc, EGFR and 20q13 loci in the no- dysplasia-dysplasia-adenocarcinoma sequence of Barrett’s esophagus Chapter 7 Association between Y-chromosomal haplotypes and susceptibility to Barrett’s esophagus Chapter 8 Summary and General discussion Appendices: Samenvatting Appendices: Acknowledgments Appendices: List of publications Appendices: Curriculum Vitae Appendices: Color figures
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