Immediate treatment, long-term impact The viral reservoir and immune response in acutely treated HIV infection

Thesis (complete) (Embargo up to 2027-02-06)

Front matter

Chapter 1: General introduction and outline of this thesis

Chapter 2: HIV-specific CD8+ T-cell proliferative response 24 weeks after early antiretroviral therapy initiation predicts the subsequent reduction of the viral reservoir

Chapter 3: HIV-specific CD8+ T-cell response drives viral evolution and loss of intact proviruses in early treated individuals (Embargo up to 2027-02-06)

Chapter 4: Long-term effect of temporary ART initiated during primary HIV-1 infection on the viral persistence

Chapter 5: Virological and immunological correlates of HIV post-treatment control after temporal antiretroviral therapy during acute HIV infection

Chapter 6: Soluble CD14 and IL-12p70 on early ART predict HIV load setpoint after treatment interruption

Chapter 7: Perceptions of rapid antiretroviral therapy initiation among participants of The Netherlands Cohort Study on Acute HIV Infection

Chapter 8: Perceptions of HIV cure and willingness to participate in HIV cure-related trials among people enrolled in the Netherlands cohort study on acute HIV infection

Chapter 9: General discussion

Summary; Nederlandse samenvatting; List of contributing authors; List of publications; PhD portfolio; Dankwoord; About the author

Stellingen