Vitiligo pathogenesis and immunotherapy of melanoma

Authors	J.G. van den Boorn
Supervisors	J.D. Bos C.J.M. Melief
Cosupervisors	R.M. Luiten
Award date	06-07-2010
ISBN	9789490371227
Number of pages	182
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Language	English
Downloads	Thesis Front cover Title pages Table of contents Chapter 1: General introduction Chapter 2: T cell avidity and tuning: the flexible connection between tolerance and autoimmunity Chapter 3: Autoimmune destruction of skin melanocytes by perilesional T cells from vitiligo patients Chapter 4: Therapeutic implications of autoimmune vitiligo T cells Chapter 5: Monobenzone induces autoimmune skin depigmentation by specific immunogenic melanocyte modulation Chapter 6: Targeting of melanosomes to MHC class-II compartments by monobenzone-induced autophagy Chapter 7: Effective melanoma immunotherapy in mice by the skin-depigmenting agent monobenzone and the adjuvants imiquimod and CpG Chapter 8: General discussion Summary Samenvatting Samenvatting voor niet-ingewijden Dankwoord List of publications Curriculum vitae Used abbreviations
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