Are quantitative attenuation measurements of blood by optical coherence tomography feasible?

Open Access
Authors
Publication date 2009
Journal Optics Letters
Volume | Issue number 34 | 9
Pages (from-to) 1435-1437
Organisations
  • Faculty of Medicine (AMC-UvA)
Abstract We present optical coherence tomography (OCT) measurements on fully physiologically oxygenated blood samples of varying hematocrit. We show that attenuation coefficients cannot be extracted quantitatively using the currently accepted models for the OCT signal from scattering media, because the confidence intervals obtained in the fitting procedure cannot be used as reliable uncertainty estimates of the attenuation coefficients. Better modeling of the hematocrit-dependent OCT signal is needed. (C) 2009 Optical Society of America
Document type Article
Language English
Published at https://doi.org/10.1364/OL.34.001435
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