The antigen receptor in the pathogenesis of B-cell non-Hodgkin's lymphomas

Thesis

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Titlepage

Contents

Chapter 1 General introduction

Chapter 2 Variable heavy chain gene analysis of follicular lymphomas: correlation between heavy chain isotype expression and somatic mutation load

Chapter 3 In situ analysis of the variable heavy chain gene of an IgM/IgG-expressing follicular lymphoma: Subclone selection rather than clonal evolution over time

Chapter 4 Molecular and functional analysis of B-cell receptors of mucosa-associated lymphoid tissue lymphomas

Chapter 5 VH Gene Analysis of Primary Cutaneous B-Cell Lymphomas: Evidence for Ongoing Somatic Hypermutation and Isotype Switching

Chapter 6 Immunoglobulin diversification in a B-CLL: Alternative splicing of heavy chain variable region as a byproduct of somatic hypermutation

Chapter 7 General discussion

Summary

Samenvatting

List of publications

Curriculum vitae

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