Hemodynamics in intracranial aneurysms

Hemodynamics are considered a risk factor for the initiation, growth and rupture of intracranial aneurysms. In this thesis several aspects of the research of hemodynamics in intracranial aneurysms are discussed. First, I discuss the need to obtain aneurysm hemodynamics in a patient-specific manner, followed by possible clinical routines for obtaining such information. Second, the strengths and limitations of presented studies and the underlying technology are discussed. Third, the main outcome of the comparison study in chapter 10 is absence of additional value of aneurysm hemodynamics for characterization of ruptured versus unruptured aneurysm. This outcome raises questions whether there still is a future for hemodynamics in rupture risk prediction, and whether additional studies are still required to determine its definitive role for this purpose.