Beyond skin deep

Beyond skin deep Exploring interactions between Borrelia and the host immune system

Authors	L.M.K. Mason
Supervisors	J.W.R. Hovius T.B.H. Geijtenbeek
Award date	12-09-2019
ISBN	9789463612951
Number of pages	169
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Language	English
Downloads	Thesis (complete) Front matter Preface and thesis outline Chapter 1: Ménage à trois: Borrelia, dendritic cells, and tick saliva interactions Chapter 2: Borrelia induces TLR-2-mediated migration of dendritic cells in a novel human ex vivo skin model of Lyme borreliosis Chapter 3: Investigating human dendritic cell immune responses to Borrelia burgdorferi Chapter 4: Borrelia miyamotoi activates human dendritic cells and elicits T cell responses Chapter 5: Rapid outer-surface protein C DNA tattoo vaccination protects against Borrelia afzelii infection Chapter 6: Borrelia burgdorferi clinical isolates induce human innate immune responses that are not dependent on genotype Chapter 7: MRP8/14 does not contribute to dissemination or inflammation in a murine model of Lyme borreliosis Chapter 8: Summary and general discussion Nederlandse samenvatting voor niet-ingewijden; List of contributing authors; List of publications; PhD portfolio; CV; References; Acknowledgements
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