Additional file 2. Evaluated approaches for clonal famility reconstruction. BcR repertoire datasets used to evaluate clonal familty reconstruction approaches. Results of outcome measures for all approaches applied to all datasets. Performance of 10 approaches applied to two samples from three simulated datasets. Heavy chain (HC) and Light chains (LC) in single cell datasets D4 (Claireaux et al, 2022) and D5 (DeKosky et al., 2013). Concordance analysis of HC-based clonal families. Shared Clonal Families. Dominant shared Clonal Families for D9.2 (single RA patient).
Publisher
Figshare
Organisations
Faculty of Science (FNWI) - Swammerdam Institute for Life Sciences (SILS)