Small GTPases : emerging targets in rheumatoid arthritis

Open Access
Authors
  • J.R. Ferreira de Abreu
Supervisors
  • P.P. Tak
Cosupervisors
  • K.A. Reedquist
Award date 11-12-2009
Number of pages 198
Organisations
  • Faculty of Medicine (AMC-UvA)
Abstract The studies provided in this thesis show that modulation of small GTPase function regulates cellular activation and inflammation in RA and animal models of the disease. Small GTPases are therefore emerging targets in RA and further studies should explore the development of novel small GTPase modulators and evaluate their potential in the treatment of patients with RA.
Document type PhD thesis
Language English
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