Aberrant DNA hypermethylation and apoptotic defects in pediatric neuroblastomas

Authors	M.M. van Noesel
Supervisors	R. Versteeg P.A. Voute
Award date	20-01-2005
ISBN	9090190260 9789090190266
Number of pages	115
Publisher	Buijten & Schipperheijn
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: GEMO
Downloads	Thesis Cover Titlepage Contents List of Selected Abbreviations Chapter 1 Introduction Pediatric neuroblastomas: genetic and epigenetic 'Danse Macabre' Chapter 2 Tumor-specific down-regulation of the TRAIL decoy receptors DcR1 and DcR2 is associated with dense promoter hypermethylation Chapter 3 The N-myc paradox: N-myc overexpression in neuroblastomas is associated with sensitivity as well as resistance to apoptosis Chapter 4 Clustering of hypermethylated genes in neuroblastoma Chapter 5 The human tissue-specific Death Receptor-3 (DR3) promoter is hypermethylated in non-expressing adult and embryonic tissues and is aberrantly methylated in non-Hodgkin's lymphoma Chapter 6 General discussion and future directions Nederlandse samenvatting Curriculum Vitae Dankwoord/Acknowledgement Cover
Permalink to this page

Back

UvA-DARE