Dynamic changes in gene expression of the cyanobacterium Synechocystis sp. PCC 6803 in response to nitrogen starvation

In this thesis we exploit the fast moving field of microarray analysis, from its early rise till a first valuable product. A newly developed microarray platform for Synechocystis permits whole-genome transcriptomics of cyanobacteria exposed to environmental stress. This brings new insights into the molecular and physiological adaptations of cyanobacteria to nitrogen limitation and nitrogen starvation. In a broader context, this work may contribute to an improved understanding of the response of aquatic microorganisms to changing environmental conditions, thus providing a deeper appreciation of the complexities of microbial life in aquatic ecosystems.