The role of APRIL in immunity and tumorigenicity

Authors	G. Hardenberg
Supervisors	J.P. Medema
Award date	24-04-2008
ISBN	9789064642418
Number of pages	191
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Cover Titlepage Contents Chapter 1 The expanding role of APRIL in cancer and immunity Chapter 2 Thymus independent class switch recombination is affected by APRIL Chapter 3 Specific TLR ligands regulate APRIL secretion by dendritic cells in a PKR-dependent manner Chapter 4 The HSPG binding domain of APRIL serves as a platform for ligand multimersation and cross-linking Chapter 5 APRIL affects antibody responses and early leukocyte infiltration, but not influenza A viral control Chapter 6 APRIL facilitates viral-induced erythroleukemia, but is dispensable for T cell immunity and lymphomagenesis Chapter 7 APRIL promotes B-1 cell-associated neoplasm Chapter 8 Summary and General Discussion Nederlandse Samenvatting Dankwoord Publications Curriculum Vitae
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