The influence of free radicals and other reactive oxygen species on pharmacological actions in the cardiovascular system

Authors	S.L.M. Peters
Supervisors	P.A. van Zwieten
Cosupervisors	M. Pfaffendorf M.C. Michel
Award date	17-02-1999
ISBN	909012408X 9789090124087
Number of pages	140
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: CRIA
Language	English
Downloads	Thesis Cover Titlepage Contents 1 General introduction 2 The influence of oxidative stress on various inotropic responses in isolated rat left atria 3 Possible mechanism of the negative inotropic effect of ά1 -adrenoceptor agonists in isolated rat left atria exposed to reactive oxygen species 4 Influence of hydrogen peroxide on adrenoceptor-mediated inotropic responses in isolated rat hearts 5 Reactive oxygen species potentiate the negative inotropic effect of cardiac M2-muscarinic receptor stimulation 6 A mitogen-activated protein kinase is involved in contractile responses of rat heart and aorta to a-adrenoceptor agonists and endothelin 7 Mechanism of reactive oxygen species-induced aortic vasoconstriction and deterioration of functional integrity 8 General discussion Summary Samenvatting Bibliography Nawoord Cover
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