In vitro activities of eight antifungal drugs against 55 clinical isolates of Fonsecaea spp.

Authors
  • J.F. Meis
Publication date 2010
Journal Antimicrobial Agents and Chemotherapy
Volume | Issue number 54 | 4
Pages (from-to) 1636-1638
Organisations
  • Faculty of Science (FNWI) - Institute for Biodiversity and Ecosystem Dynamics (IBED)
Abstract The in vitro activities of eight antifungal drugs against clinical isolates of Fonsecaea pedrosoi (n = 21), Fonsecaea monophora (n = 25), and Fonsecaea nubica (n = 9) were tested. The resulting MIC90s for all strains (n = 55) were as follows, in increasing order: posaconazole, 0.063 µg/ml; itraconazole, 0.125 µg/ml; isavuconazole, 0.25 µg/ml; voriconazole, 0.5 µg/ml; amphotericin B, 2 µg/ml; caspofungin, 2 µg/ml; anidulafungin, 2 µg/ml; and fluconazole, 32 µg/ml.
Document type Article
Language English
Published at https://doi.org/10.1128/AAC.01655-09
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