Modulating T cell homeostasis via TNF and TNFR superfamily members : characterization and function of effector &amp; regulatory T cells

Modulating T cell homeostasis via TNF and TNFR superfamily members : characterization and function of effector & regulatory T cells

Authors	R.W. van Olffen
Supervisors	R.A.W. van Lier
Cosupervisors	M.A. Nolte
Award date	20-11-2009
ISBN	9789090247274
Number of pages	230
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Language	English
Downloads	Thesis Title pages Contents Chapter 1: General introduction Chapter 2: GITR triggering induces expansion of both effector and regulatory CD4+ T cells in vivo Chapter 3: Enhanced GITR/GITRL interactions reduce IgG3 and enhance IgA secretion Chapter 4: CD70 driven chronic T cell stimulation decreases inflammation-induced macrophage accumulation by enhancing apoptosis Chapter 5: Protective CD8 T cell memory is impaired during chronic CD70-driven co-stimulation Chapter 6: Function of CD27 in helper T cell differentiation Chapter 7: Timing and tuning of CD27-CD70 interactions : the impact of signal strength in setting the balance between adaptive responses and immunopathology English summary Nederlandse samenvatting Publications Dankwoord
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