Re-scan confocal microscopy scanning twice for better resolution

Open Access
Authors
Publication date 2013
Journal Biomedical optics express
Volume | Issue number 4 | 11
Pages (from-to) 2644-2656
Number of pages 13
Organisations
  • Faculty of Medicine (AMC-UvA)
  • Faculty of Science (FNWI) - Swammerdam Institute for Life Sciences (SILS)
Abstract We present a new super-resolution technique, Re-scan Confocal Microscopy (RCM), based on standard confocal microscopy extended with an optical (re-scanning) unit that projects the image directly on a CCD-camera. This new microscope has improved lateral resolution and strongly improved sensitivity while maintaining the sectioning capability of a standard confocal microscope. This simple technology is typically useful for biological applications where the combination high-resolution and high-sensitivity is required.
Document type Article
Note With Supplementary Material
Language English
Published at https://doi.org/10.1364/BOE.4.002644
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Re-scan confocal microscopy (Final published version)
Supplementary materials
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