Explaining unexplained hypoglycemia: How LC-MS/MS can help

Open Access
Authors
Publication date 08-2022
Journal Practical Laboratory Medicine
Article number e00291
Volume | Issue number 31
Number of pages 4
Organisations
  • Faculty of Science (FNWI) - Van 't Hoff Institute for Molecular Sciences (HIMS)
Abstract Explaining hypoglycaemia, especially in patients without diabetes mellitus, is challenging. Here we present a case, where the added value for clinical diagnosis of insulin determination with liquid chromatography-mass spectrometry (LC-MS/MS) is shown. By the use of LC-MS/MS the different insulin analogues can be identified. The confirmation of an insulin analogue present during hypoglycaemia facilitated in our case the discussion with the patient and his family about what happened.
Document type Article
Language English
Published at https://doi.org/10.1016/j.plabm.2022.e00291
Other links https://www.scopus.com/pages/publications/85134156221
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Explaining unexplained hypoglycemia (Final published version)
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