Identification and characterization of human Polycomb-group proteins.

Authors	D.P.E. Satijn
Supervisors	R. van Driel
Cosupervisors	A.P. Otte
Award date	12-01-2000
Number of pages	110
Organisations	Faculty of Science (FNWI) - Swammerdam Institute for Life Sciences (SILS)
Document type	PhD thesis
Note	Research conducted at: NWI
Language	English
Downloads	Thesis Cover Titlepage Contents CHAPTER 1 General Introduction CHAPTER 2 Identification and characterization of interactions between the vertebrate Polycomb-group protein BMI1 and human homologs of Polyhomeotic. CHAPTER 3 RING1 is associated with the Polycomb-group protein complex and acts as a transcriptional repressor. CHAPTER 4 Interference with the expression of a novel human Polycomb protein, HPC2, results in cellular transformation and apoptosis. CHAPTER 5 RING1 interacts with multiple Polycomb-group proteins and displays tumorigenic activity. CHAPTER 6 Discussion Summary Samenvatting List of publications Curriculum Vitae Dankwoord Cover
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