Cardioprotection with helium and anesthetics in healthy and diseased myocardium

Authors	R. Huhn
Supervisors	W.S. Schlack M.W. Hollmann
Cosupervisors	B. Preckel N.C. Hauck
Award date	26-05-2009
Number of pages	187
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Language	English
Downloads	Thesis Cover Title pages Contents Chapter 1: Introduction Chapter 2: Physiological levels of glutamine prevent morphine induced preconditioning in the isolated rat heart Chapter 3: Helium-induced late preconditioning in the rat heart in vivo Chapter 4: Postconditioning by xenon and hypothermia in the rat heart in vivo Chapter 5: Blockade of anaesthetic induced preconditioning in the hyperglycaemic myocardium : the regulation of different mitogen activated protein kinases Chapter 6: Hyperglycaemia blocks Sevoflurane-induced postconditioning in the rat heart in vivo : cardioprotection can be restored by blocking the mitochondrial permeability transition pore Chapter 7: Cyclosporine A administered during reperfusion fails to restore cardioprotection in prediabetic Zucker obese rats in vivo Chapter 8: Helium-induced early preconditioning and postconditioning are abolished in obese Zucker rats in vivo Chapter 9: Helium-induced preconditioning in young and old rat heart : impact of mitochondrial Ca2+ -sensitive potassium channel activation Chapter 10: Main conclusions and general discussion Summary Nederlandse samenvatting Acknowledgment About the author
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