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SIV envelope evolution and virus virulence

Open Access
Authors
  • P.J.S. Valli
Supervisors
  • J. Goudsmit
Cosupervisors
  • J.L. Heeney
Award date 07-06-2000
Number of pages 110
Organisations
  • Faculty of Medicine (AMC-UvA)
Document type PhD thesis
Note Research conducted at: Infectieziekten
Language English
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Thesis
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Titlepage
Contents
Chapter 1 SIV and HIV: A General Introduction
Chapter 2 Phylogenetic Analysis using Likelihood Mapping and Quartet Puzzling of the Common Ancestry of the SIVsm/HIV-2 and SIVcpz/HIV-1 Clusters
Chapter 3 Genotypic Variation in SIVsm DeltaB670 Env During the Shift to High Virulence
Chapter 4 Shortening of the Symptom-Free Period in Rhesus Macaques Is Associated with Decreasing Nonsynonymous Variation in the env Variable Regions of Simian Immunodeficiency Virus SIVsm during Passage
Chapter 5 Structured-Tree Topology and Adaptive Evolution of the Simian Immunodeficiency Virus SIVsm Envelope during Serial Passage in Rhesus Macaques According to Likelihood Mapping and Quartet Puzzling
Chapte 6 Increased heterogeneity of SIVsm env Associated with Low Viral Load in Macaca mulatta
Chapter 7 General Disscussion
Chapter 8 Summary Samenvatting
Dankwoord
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