Anthracycline cardiotoxity in childhood cancer. Frequency, risk factors, and early detection

Thesis

Cover

Titlepage

Contents

Introduction

1 Clinical cardiotoxicity

1.1 Frequency and risk factors of anthracycline-induced clinical heart failure in children: a systematic review

1.2 Anthracycline induced clinical heart failure in a cohort of 607 children: a long term follow-up study

2 Subclinical cardiotoxicity

2.1 Subclinical cardiotoxicity after anthracycline therapy in children: a systematic review

2.2 A longitudinal echocardiographic study in children treated with anthracyclines

3 Early detection

3.1 Indium-111 antimyosin scintigraphy in the early detection of heart damage after anthracycline therapy in children

3.2 Reproducibility of the assessment of indium-111 antimyosin scintigraphy in children

3.3 Troponin T in the first 24 hours after administration of chemotherapy and the detection of myocardial damage in children

Summary

General discussion

Samenvatting

Nawoord

Stellingen behorend bij het proefschrift

Cover