Inflammation in chronic obstructive pulmonary disease : its assessment and the effects of corticosteroids

Authors	M. Boorsma
Supervisors	H.M. Jansen
Cosupervisors	R.E. Jonkers R. Lutter
Award date	17-12-2008
ISBN	9789090235998
Number of pages	215
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Cover Title pages Table of contents Chapter 1: General introduction Chapter 2: Long term effects of budesonide on inflammatory status in COPD Chapter 2 addendum: Prednisolone effects on the numbers of glucocorticosteroid receptor α and β subtypes and on inflammatory parameters in bronchoalveolar lavage, in sputum and peripheral blood Chapter 3: Repeatability of inflammatory parameters in induced sputum of COPD patients Chapter 4: Improved validity of cellular and molecular biomarkers from whole induced sputum in asthma and COPD Chapter 4 appendix: Supplementary figures Chapter 5: Inflammatory parameters and imminent exacerbations in COPD patients Chapter 6: Evidence of the in vivo esterification of budesonide in human airways Chapter 7: Pulmonary granzyme B+ cytotoxic CD8+ T cells and sputum granzyme B relate to severity of airflow limitation Chapter 7 appendix: Supplementary figures Chapter 8: General discussion Summary Nederlandse samenvatting Abbreviations List of publications Dankwoord Curriculum vitae
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