Aptamer optical biosensor without bio-breakage using upconversion nanoparticles as donors

Authors
  • K. Song
  • X. Kong
  • X. Liu
  • Y. Zhang
Publication date 2012
Journal Chemical Communications
Volume | Issue number 48 | 8
Pages (from-to) 1156-1158
Organisations
  • Faculty of Science (FNWI) - Van 't Hoff Institute for Molecular Sciences (HIMS)
Abstract LRET-based optical biosensor of an aptamer-upconversion conjugate was constructed. It is demonstrated that photosensitized breakage and damage of aptamers are eliminated by employing UCNPs as donors, and the as-designed biosensor is specific and sensitive in the detection of ATP.
Document type Article
Language English
Published at
https://doi.org/10.1039/c2cc16817k (Final published version)
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