Artificial metalloenzymes through cysteine-selective conjugation of phosphines to photoactive yellow protein
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| Publication date | 2010 |
| Journal | ChemBioChem |
| Volume | Issue number | 11 | 9 |
| Pages (from-to) | 1236-1239 |
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| Abstract | Pinning phosphines on proteins: A method for the cysteine-selective bioconjugation of phosphines has been developed. The photoactive yellow protein has been site-selectively functionalized with phosphine ligands and phosphine transition metal complexes to afford artificial metalloenzymes that are active in palladium-catalysed allylic nucleophilic substitution reactions. |
| Document type | Article |
| Language | English |
| Published at |
https://doi.org/10.1002/cbic.201000159
(Final published version)
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