Metabolite-Induced Protein Expression Guided by Metabolomics and Systems Biology

Authors
Publication date 06-02-2018
Journal Cell Metabolism
Volume | Issue number 27 | 2
Pages (from-to) 270-272
Number of pages 3
Organisations
  • Faculty of Science (FNWI) - Swammerdam Institute for Life Sciences (SILS)
Abstract

Metabolomics combined with systems biology can be used to identify endogenous metabolites that modulate protein expression. Recent examples include the 2-fold enhancements of pertussis toxin protein in vaccine production and myelin basic protein expression in oligodendrocyte maturation; both applied a metabolomics-systems strategy to identify active metabolites.

Document type Article
Language English
Published at https://doi.org/10.1016/j.cmet.2018.01.002
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