The transcription factor KLF2 in vascular biology

The transcription factor KLF2 in vascular biology

Authors	R.A. Boon
Supervisors	H. Pannekoek A.J.G. Horrevoets
Award date	23-09-2008
ISBN	9789090232584
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Cover Titlepage Contents Chapter 1 General introduction Chapter 2 KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium Chapter 3 KLF2 suppresses TGF-β signaling in endothelium through induction of Smad7 and inhibition of AP-1 Chapter 4 Prolonged shear stress and KLF2 suppress constitutive pro-inflammatory transcription through inhibition of ATF2 Chapter 5 KLF2 primes the antioxidant transcription factor Nrf2 for activation in endothelial cells Chapter 6 Endothelial KLF2 regulates mitogen activated protein kinase signaling through RhoA and the actin cytoskeleton Chapter 7 KLF2 increases endothelial progenitor cells and is reduced by aging/senescence and by hyperglycemia in a p38-dependent manner Chapter 8 General discussion Chapter 9 Summary & Samenvatting Chapter 10 Curriculum Vitae & Acknowledgements Supplement : Supplemental figures of the PhD thesis “The transcription factor KLF2 in vascular biology” Supplemental tables - Chapter 2 - induced genes Supplemental tables - Chapter 2 - repressed genes Supplemental tables - Chapter 4 - tables I and II Supplemental tables - Chapter 5 - table I Supplemental tables - Chapter 5 - table IIA Supplemental tables - Chapter 5 - table IIB Supplemental tables - Chapter 5 - table IIIA Supplemental tables - Chapter 5 - table IIIB Supplemental tables - Chapter 6 - table I Supplemental tables - Chapter 6 - table II
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The transcription factor KLF2 in vascular biology