A high-performance electrochemical biosensor using an engineered urate oxidase

Open Access
Authors
Publication date 30-05-2023
Journal Chemical Communications
Volume | Issue number 59 | 52
Pages (from-to) 8071-8074
Organisations
  • Faculty of Science (FNWI) - Van 't Hoff Institute for Molecular Sciences (HIMS)
Abstract

We constructed a high-performance biosensor for detecting uric acid by immobilizing an engineered urate oxidase on gold nanoparticles deposited on a carbon-glass electrode. This biosensor showed a low limit-of-detection (9.16 nM), a high sensitivity (14 μA/μM), a wide range of linearity (50 nM-1 mM), and more than 28 days lifetime.

Document type Article
Note With supplementary file.
Language English
Published at https://doi.org/10.1039/d3cc01869e
Other links https://www.scopus.com/pages/publications/85162097791
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d3cc01869e (Final published version)
Supplementary materials
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