Homeobox genes in neuroblastoma

Authors	I.M. Revet
Supervisors	R. Versteeg
Cosupervisors	D. Geerts
Award date	20-05-2010
ISBN	9789090253114
Number of pages	175
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Language	English
Downloads	Thesis Cover Title pages Contents Chapter 1: Introduction to neuroblastoma and scope of this thesis Chapter 2: The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta- Notch pathway in neuroblastoma Chapter 3: MSX1 induces the Wnt pathway antagonist genes DKK1,DKK2, DKK3, and SFRP1 in neuroblastoma cells, but does not block Wnt3 and Wnt5A signaling to DVL3 Chapter 4: Analysis of TALE homeobox genes in neuroblastic tumors reveals a major role for MEIS1 in differentiation and cell survival Chapter 5: MSX1 is induced by NOTCH3 and mediates a proliferation arrest module, but not a motility module activated by NOTCH3 in neuroblastoma Chapter 6: Summarizing discussion Chapter 7: Nederlandse samenvatting Dankwoord Curriculum vitae List of publications
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