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  2. Lymphoid development; a dynamic interplay of timing and dosing

Lymphoid development; a dynamic interplay of timing and dosing

Open Access
Authors
  • A.U.G. van Lent
Supervisors
  • H. Spits
Cosupervisors
  • N. Legrand
Award date 02-09-2009
ISBN
  • 9789090244952
Number of pages 285
Organisations
  • Faculty of Medicine (AMC-UvA)
Document type PhD thesis
Language English
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Cover
Table of contents
Chapter 1: General introduction
Chapter 2: Human thymus regeneration and T cell reconstitution
Chapter 3: In vivo modulation of gene expression by lentiviral transduction in “Human Immune system” Rag2-/-gc-/- mice
Chapter 4: IL-7 enhances human T cell development in “Human Immune System” Rag2-/-gc-/- mice without affecting peripheral T cell homeostasis
Chapter 5: Thymic stromal lymphopoietin (TSLP) induces early human B cell proliferation and differentiation
Chapter 6: High levels of thymic stromal lymphopoietin can compensate IL-7 deficiency in human T cell development and increase human CD4+CD25hi T cell formation
Chapter 8: The Id2 induced block in T cell generation is overcome by TCRab overexpression
Chapter 9: General discussion
Summary
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Dankwoord
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