Plakin interactions in the hemidesmosome

Thesis

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Titlepage

Table of contents

Chapter 1 Hemidesmosomes: Molecular organization and their importance for cell adhesion and disease

Chapter 2 Two different mutations in the cytoplasmic domain of the integrin β4 subunit in non-lethal forms of epidermolysis bullosa prevent interaction of β4 with plectin

Chapter 3 Analysis of the interactions between BP180, BP230, plectin and the integrin α6β4 important for hemidesmosome assembly

Chapter 4 A single β4 subunit can bind two plectin molecules and evidence for a role of plectin in activation of the β4 cytoplasmic domain

Chapter 5 Specificity of binding of the plectin Actin Binding Domain to β4 integrin

Summary

Samenvatting

Dankwoord

Curriculum vitae

List of Publications

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