Proteolytic activation of bovine brain protein with phosphatidylinositol transfer activity
| Authors |
|
|---|---|
| Publication date | 1990 |
| Journal | FEBS Letters |
| Volume | Issue number | 276 |
| Pages (from-to) | 123-126 |
| Number of pages | 4 |
| Organisations |
|
| Abstract | We have purified a 38 kDa protein from bovine brain which is cross-reactive with an affinity purified antibody against the 35 kDa phosphatidylino-sitol transfer protein from the same source. Controlled trypsinization of the 38 kDa protein yielded an immunoreactive protein of 35 kDa which displayed a 6-fold increase in phosphatidylinositol transfer activity and a IO-fold higher affinity for this phospholipid. The possibility that the 38 kDa protein is a precursor of the phosphatidylinositol transfer protein is discussed.(C) 1990 Elsevier Science B.V. All rights reserved. |
| Document type | Article |
| Published at |
https://doi.org/10.1016/0014-5793(90)80523-L
(Final published version)
|
| Permalink to this page | |
