Regulation of structural plasticity and neurogenesis during stress and diabetes; protective effects of glucocorticoid receptor antagonists

Open Access
Authors
Publication date 2011
Host editors
  • A.G. Gravanis
  • S.H. Mellon
Book title Hormones in neurodegeneration, neuroprotection, and neurogenesis
ISBN
  • 9783527326273
Pages (from-to) 103-120
Number of pages 375
Publisher Weinheim: Wiley-VCH
Organisations
  • Faculty of Science (FNWI) - Swammerdam Institute for Life Sciences (SILS)
Abstract In this chapter, we will review changes in structural plasticity of the adult hippocampus during stress and exposure to glucocorticoids (GCs). We further discuss the protective and normalizing role of glucocorticoid receptor (GR) antagonist treatment under these conditions and its implications for disorders such as depression and diabetes mellitus.
Document type Chapter
Language English
Published at
https://doi.org/10.1002/9783527633968.ch6 (Final published version)
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