Concentration-effect relations of anti-asthma medications. Studies on inflammation markers

Authors	M.G.M. Derks
Supervisors	C.J. van Boxtel
Award date	01-10-1999
Number of pages	199
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Immunologie
Language	English
Downloads	Thesis Cover Titlepage Contents Chapter 1: The contribution of pharmacokinetic-pharmacodynamic modelling to the study of anti-inflammatory agents Chapter 2: Combined drug action; introduction to kinetic-dynamic modelling Chapter 3: Pharmacokinetic/pharmacodynamic modelling of the eosinopenic and hypokalemic effects of formoterol and theophylline combination in man Chapter 4: Prevention by theophylline of beta-2-receptor down regulation in healthy subjects Chapter 5: Biphasic effect-time courses in man after formoterol inhalation: eosinopenic and hypokalemic effects and inhibition of allergic skin reactions Chapter 6: Urinary excretion of formoterol enantiomers: pharmacokinetics in healthy subjects after inhalation of formoterol racemate Chapter 7: Differential kinetics of formoterol enantiomers and the effect on plasma potassium and pulmonary function in asthma patients following a single inhaled dose Chapter 8: The effect of hydrocortisone on plasma tyrosine concentration and lymphocyte counts in healthy subjects Chapter 9: Summary Nederlandse Samenvatting Nawoord Cover
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