Regulation of cardiovascular GPCR signalling

Authors	M.C. Balk
Supervisors	M.C. Michel
Cosupervisors	A.E. Alewijnse S.L.M. Peters
Award date	21-09-2009
ISBN	9789085595564
Number of pages	160
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Language	English
Downloads	Thesis Cover Title pages Table of contents Chapter 1: Regulation of G protein-coupled receptor signalling : focus on the cardiovascular system and regulator of G protein signalling proteins : a general introduction Chapter 2: Extracellular S1P disappearance : effect on signalling potency Chapter 3: Differential agonist-induced regulation of the sphingosine-1-phosphate receptor subtypes 1 and 3 (S1P1 and S1P3) Chapter 4: S1P receptor signalling and RGS proteins : expression and function in vascular smooth muscle cells and transfected CHO cells Chapter 5: Sphingosine-1-phosphate regulates RGS2 and RGS16 mRNA expression in vascular smooth muscle cells Chapter 6: LPS differentially affects vasoconstrictor responses : a potential role for RGS16? Chapter 7: General discussion Summary Samenvatting Dankwoord List of publications Curriculum vitae Appendix: Pitfalls in the normalization of real-time polymerase chain reaction data
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