Identification and characterization of the Frat1 proto-oncogene

Authors	J.M.M. Jonkers
Supervisors	A.J.M. Berns
Award date	29-10-1999
Number of pages	111
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Language	English
Downloads	Thesis Cover Titlepage Contents Chapter 1: Retroviral insertional mutagenesis as a strategy to identify cancer genes Chapter 2: Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas. Chapter 3: Overexpression of Frat1 in transgenic mice leads to glomerulosclerosis and nephrotic syndrome, and provides direct evidence for the involvement of Frat1 in lymphoma progression. Chapter 4: In vivo analysis of Frat1 deficiency suggests compensatory activity of Frat3. UBA003000172_008.pdf Summary Samenvatting in het Nederlands Dankwoord Curriculum vitae Publications Abbreviations Cover
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