Antibiotic Killing through Incomplete DNA Repair
| Authors | |
|---|---|
| Publication date | 01-2018 |
| Journal | Trends in Microbiology |
| Volume | Issue number | 26 | 1 |
| Pages (from-to) | 2-4 |
| Number of pages | 3 |
| Organisations |
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| Abstract |
Two recent studies show that incomplete repair of DNA damage due to oxidized nucleotides is crucial for reactive oxygen species (ROS)-related antimicrobial lethality. Using widely different experimental approaches they both reach the same conclusions on the role of downstream ROS production in cell killing upon exposure to bactericidal antimicrobials. |
| Document type | Article |
| Language | English |
| Published at |
https://doi.org/10.1016/j.tim.2017.11.006
(Final published version)
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| Permalink to this page | |