Risk assessment and prevention of spontaneous preterm birth

Preterm birth is the most important cause of neonatal mortality and morbidity worldwide. The pathogenesis of preterm birth is complex and largely unknown. Despite extensive research, preterm birth remains relatively hard to predict and difficult to prevent. It is a major clinical and scientific challenge in the obstetric healthcare. This thesis describes various risk factors in different populations of pregnant women that contribute to the risk prediction of preterm birth. In addition, current available and potential novel preventive management strategies in women at risk for spontaneous preterm birth are discussed.