Cell-derived microparticles : composition and function

Thesis

Title page

Contents

Chapter 1: General introduction, aims and outline of this thesis

Chapter 2: Measuring circulating cell-derived microparticles : a flow cytometric method of microparticle analysis

Chapter 3: The phospholipid composition and cholesterol content of platelet-derived microparticles : a comparison with platelet membrane fractions

Chapter 4: Human cell-derived microparticles promote thrombus formation in vivo in a tissue factor-dependent manner

Chapter 5: Phospholipid composition of in vitro endothelial microparticles and their in vivo thrombogenic properties

Chapter 6: P-selectin- and CD63-exposing platelet microparticles reflect platelet activation in peripheral arterial disease and myocardial infarction

Chapter 7: Plasma markers of coagulation and endothelial activation in Fabry disease : impact of renal impairment

Chapter 8: Targeting complement in rheumatoid arthritis

Chapter 9: Activated complement components and complement activator molecules on the surface of cell-derived microparticles in patients with rheumatoid arthritis and healthy individuals

Chapter 10: Complement activation on the surface of cell-derived microparticles during cardiac surgery with cardiopulmonary bypass : is retransfusion of pericardial blood harmful?

Chapter 11: Complement activation on cell-derived microparticles in myocardial infarction is mediated by immunoglobulin G and not C-reactive protein

Chapter 12: Cell-derived microparticles and complement activation in preeclampsia versus normal pregnancy

Summary

Samenvatting

Acknowledgements

Curriculum vitae

List of publications

Stellingen