RESILIENCE by design ten principles to guide chemistry in a volatile world

The unexpected large-scale electrical blackout across the Iberian Peninsula in April 2025 served as a stark reminder of our growing dependency on a stable electricity supply and the inherent vulnerability of electrified systems—including chemical manufacturing, scientific research, and education. Scientists working in green and sustainable chemistry are increasingly committed to electrification and net-zero industrial practices. However, we must also ensure that these processes are resilient to disruption. In this article, we propose ten principles for more resilient chemistry, designed to add to the discussion and to stimulate further research into how chemistry can remain both sustainable and robust in the face of volatility in energy supply, resource constraints, and geopolitical instability. We call on the global chemical community to reflect on the implications of such disruptions—not only for industrial production, but also for scientific gatherings, laboratory research, and the future of chemistry education.