Motion compensation for 4D PET/CT

Authors	M.F. Kruis
Supervisors	M.B. van Herk
Cosupervisors	J.B. van de Kamer J.J. Sonke
Award date	18-12-2014
ISBN	9789462594661
Number of pages	97
Organisations	Faculty of Medicine (AMC-UvA)
Abstract	This thesis addresses the effects of respiratory motion on PET/CT data, in terms of signal blurring and incorrect attenuation correction. Respiratory motion leads to overestimation of the tumour volume and incorrect SUV values. We develop a framework for respiratory motion compensation of 4D PET-CT data and demonstrate that the techniques are applicable for both lung and liver data.
Document type	PhD thesis
Note	Research conducted at: Netherlands Cancer Institute Amsterdam
Language	English
Downloads	Thesis (complete) Front matter 1: Introduction 2: PET motion compensation for radiation therapy using a CT-based mid-position motion model: Methodology and clinical evaluation 3: Clinical evaluation of respiration-induced attenuation uncertainties in pulmonary 3D PET/CT 4: Registration accuracy and image quality of time averaged mid-position CT scans for liver SBRT 5: CT-based motion compensation of rapidly acquired 4D PET of the liver: A feasibility study 6: 4D CT amplitude binning for the generation of a time-averaged 3D mid-position CT scan 7: General discussion and conclusion Back matter
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