Enantioselective adsorption of ibuprofen and lysine in metal-organic frameworks

Open Access
Authors
  • R. Bueno-Perez
  • A. Martin-Calvo
  • P. Gómez-Álvarez
  • J.J. Gutiérrez-Sevillano
Publication date 2014
Journal Chemical Communications
Volume | Issue number 50 | 74
Pages (from-to) 10849-10852
Organisations
  • Faculty of Science (FNWI) - Van 't Hoff Institute for Molecular Sciences (HIMS)
Abstract This study reveals the efficient enantiomeric separation of bioactive molecules in the liquid phase. Chiral structure HMOF-1 separates racemic mixtures whereas heteroselectivity is observed for scalemic mixtures of ibuprofen using non-chiral MIL-47 and MIL-53. Lysine enantiomers are only separated by HMOF-1. These separations are controlled by the tight confinement of the molecules.
Document type Article
Note With supplementary information
Language English
Published at https://doi.org/10.1039/c4cc03745f
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Enantioselective adsorption of ibuprofen (Final published version)
Supplementary materials
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