Legionnaires’ disease in the Netherlands, 1998-2006

Thesis

Cover

Titlepage

Contents

Chapter 1. General introduction

Part 1. Epidemiology

Chapter 2. A large outbreak of Legionnaires' disease at a flower show, the Netherlands, 1999

Chapter 3. Risk factors for sporadic community-acquired Legionnaires' disease. A three-year national case-control study

Chapter 4. Use of surface water in drinking water production associated with municipal Legionnaires' disease incidence

Part 2. Transmission

Chapter 5. Legionnaires' disease and gardening

Chapter 6. Genotypic comparison of clinical Legionella isolates and patient-related environmental strains in the Netherlands, 2002-2006

Part 3. Laboratory diagnosis

Chapter 7. Diagnosis of Legionella infection in Legionnaires' disease

Chapter 8. Sensitivity of three urinary antigen tests associated with clinical severity in a large outbreak of Legionnaires' disease in the Netherlands

Chapter 9. The sensitivity of three serum antibody tests in a large outbreak of Legionnaires' disease in the Netherlands

Part 4. Control and prevention

Chapter 10. Outbreak detection and secondary prevention of Legionnaires' disease in the Netherlands. A systematic approach

Chapter 11. General discussion

Summary

Samenvatting

Acknowledgements

Curriculum Vitae

Publications

Figures