PCI of complex coronary lesions, new stent technologies, and clinical outcomes

Front cover

Title pages

Table of contents

Chapter 1: General introduction and outline of the thesis

Chapter 2.1: A retrospective analysis of consecutive patients undergoing nonurgent percutaneous coronary intervention comparing bare metal stents with drug-eluting stents using the National Institute for Clinical Excellence criteria

Chapter 2.2: Long-term follow-up after non-urgent percutaneous coronary intervention in unprotected left main coronary arteries

Chapter 2.3: One-year clinical outcome after treatment of bare-metal stent in-stent restenosis with the paclitaxel-eluting stent in an unselected cohort

Chapter 3.2: One-year clinical outcome after provisional T-stenting for bifurcation lesions with the endothelial progenitor cell capturing stent compared with the bare-metal stent

Chapter 3.3: Twelve-month clinical outcomes after coronary stenting with the Genous™ bio-engineered R stent™ in patients with a bifurcation lesion from the e-HEALING registry

Chapter 4.2: Genous™ endothelial progenitor cell capturing stent versus the Taxus Liberté stent in patients with de novo coronary lesions with a high-risk of coronary restenosis: a randomized, single-centre, pilot study

Chapter 4.3: Two-year follow-up of the Genous™ endothelial progenitor cell capturing stent versus the Taxus Liberté stent in patients with de novo coronary lesions with a high-risk of coronary restenosis: a randomized, single-center, pilot study

Chapter 4.4: Design and rationale of the TRI-stent adjudication study (TRIAS) program

Chapter 4.5: One-year outcome of the TRIAS high risk study; a multi-center, randomized trial comparing Genous™ EPC capturing stents with drug-eluting stents

Chapter 4.6: One-year clinical outcome in an unselected patient population treated with the Genous™ endothelial progenitor cell capturing stent

Chapter 4.7: Significant intimal hyperplasia regression between 6 and 18 months following Genous™ endothelial progenitor cell capturing stent placement

Chapter 5.3: Two-year clinical, angiographic, and intravascular ultrasound follow-up of the XIENCE V everolimus-eluting stent in the treatment of patients with de novo native coronary artery lesions: the SPIRIT II trial

Chapter 6.1: Multiple biomarkers at admission significantly improve the prediction of mortality in patients undergoing primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction

Chapter 6.2: Cystatin C for enhancement of risk stratification in patients undergoing non-urgent percutaneous coronary intervention

Chapter 6.3: Toll-like receptor 4 gene polymorphisms show no association with the risk of clinical or angiographic restenosis after percutaneous coronary intervention

Chapter 6.4: p27kip1-838C>A single nucleotide polymorphism is associated with restenosis risk after coronary stenting and modulates p27kip1 promoter activity

Chapter 7: Summary and conclusions

Chapter 8: Samenvatting en conclusies

List of publications

Dankwoord

Curriculum vitae