Targeted labeling of early-​stage tumor spheroid in chorioallantoic membrane model with upconversion nanoparticles

Targeted labeling of early-stage tumor spheroid in chorioallantoic membrane model with upconversion nanoparticles

Authors	K. Liu J.A. Holz Y. Ding X. Liu Y. Zhang L. Tu X. Kong B. Priem A. Nadort S.A.G. Lambrechts M.C.G. Aalders W.J. Buma Y. Liu H. Zhang
Publication date	2015
Journal	Nanoscale
Volume \| Issue number	7 \| 5
Pages (from-to)	1596-1600
Organisations	Faculty of Science (FNWI) - Van 't Hoff Institute for Molecular Sciences (HIMS) Faculty of Medicine (AMC-UvA)
Abstract	In vivo detection of cancer at early-stage, i.e. smaller than 2 mm, is a challenge in biomedicine. In this work target labeling of early-stage tumor spheroid (∼500 μm) is realized for the first time in chick embryo chorioallantoic membrane (CAM) model with monoclonal antibody functionalized upconversion nanoparticles (UCNPs-mAb).
Document type	Article
Note	with supplementary information
Language	English
Published at	https://doi.org/10.1039/c4nr05638h
Published at	http://dx.doi.org/10.1039/C4NR05638H
Downloads	Targeted labeling (Final published version)
Supplementary materials	Targeted labeling suppl
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